Will Anyone Crack the Obesity Drug Market?

Published 01 February 2011

  • 114 pages
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Will Anyone Crack the Obesity Drug Market?

Following the FDA’s decision on Orexigen’s Contrave, the question is: Will a successful obesity drug market ever develop?

Use this report to:

  • Understand the state of play with Orexigen’s Contrave
  • Review the prevalence and impact of obesity
  • Evaluate the therapeutic approaches being undertaken
  • Critically assess and compare the approach and potential of products in clinical research with our unique product scoring

Around one in three of the global adult population and more than 20 million children under five are overweight according to the World Health Organization. Around 10% of adults are obese. In the US, an estimated 44.2% of males and 48.3% of females have a body mass index (BMI) of 30 or more and are classified as obese.

Orexigen’s Contrave: possibly a new chapter – but when?

In December 2010, the FDA’s Endocrinologic and Metabolic Drugs Advisory Committee voted positively in favour of Orexigen’s naltrexone sustained-release (SR) and bupropion SR combination, Contrave. The market was then surprised when the FDA did not approve the drug, asking instead for further clinical trials. If Contrave had been approved, it would have been the first new pharmacological treatment for obesity for more than a decade and would have immediately doubled the choice of available therapies; currently the only prescription drug that remains approved for obesity in the US and EU is Roche’s Xenical (orlistat), a low-dose OTC version of which is marketed by GlaxoSmithKline as alli.

Report contents summary

  • Executive summary
  • Current market
  • Future market
  • Background information
  • Product analysis by phase of development

This new report Will Anyone Crack the Obesity Drug Market, (published February 2011) provides a complete review of this difficult to develop area.

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